Say your characters have to go on a long trip together. This could be your opportunity to force characters together who'd otherwise never stick around each other, or your chance to go all soap opera on some characters who thought they liked each other. Strangers might learn that one of them is a serial killer, while friends might learn that the village idiot isn't such a big dummy afterall. All while facing starvation, cabin fever, etc.
What it comes down to is, which group would you rather screw with?
Feel free to answer/ramble in the comments. If the question inspires a Flash Friday or something similar, feel free to link to your story in the comments and please link back to here on the applicable webpage.
Ready. Set. GO.